Difference in IVF outcome and pregnancy rate in triggering ovulation by rHCG vs uHCG

Abstract

Historically, urinary human chorionic gonadotropin (uHCG) has been used as an alternative to LH to induce final oocyte maturation in women undergoing IVF. This retrograde chart review study was done at Medcare Fertility Center, Dubai, UAE between April 2016 to July 2017 to know the difference in IVF outcome and pregnancy rate in triggering ovulation by rHCG vs uHCG.

Total 117 women with poor ovarian response were included in this study. Embryo transfer rate for the recipient of Pregnyl and Ovitrelle was 50.77% and 51.92% respectively. The clinical pregnancy rate for Pregnyl vs Ovitrelle was 15.38% and 16.92% respectively. Positive βHCG was noted in 22.22% participants.

Large-scale multi-center RCT is required to predict the outcomes more accurately.