A Novel Β, Β -Diphenyl Propionic Acid Amide Derivatives Showing Anti-Inflammatory And Anticonvulsant Activity

Abstract

A series of β,β-Diphenyl Propionic acid amides were synthesized in order to obtain new compounds with
potential anti-inflammatory and anticonvulsants activity. The structures of new compounds are supported
by IR and 1HNMR spectral data. These derivatives were then tested for a general profile of activities as
anti – inflammatory using carrageenan induced rat paw edema method and anticonvulsants activity using
maximal electroshock seizures method and in this investigation a significant level of anti-inflammatory
and anticonvulsants activity was illustrated.